Diagnostic Atlas of Non-Neoplastic Lung Disease

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Sample Chapter: Chapter 1

Diagnostic Atlas of Non-Neoplastic Lung Disease

SKU# 9781620700648

A Practical Guide for Surgical Pathologists

Author: Anna-Luise A. Katzenstein MD

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    Diagnostic Atlas of Non-Neoplastic Lung Disease provides the practicing pathologist with the tools necessary to synthesize diagnoses in biopsy and surgical specimens of non-neoplastic lung disease. Classification of non-neoplastic lung disease has become increasingly complex, especially in diffuse lung diseases where terminology has been changing and clinical and radiologic input is advocated for diagnosis. As a result, general surgical pathologists may feel ill-equipped to interpret such specimens.

    In this heavily illustrated and concisely written book, Dr. Katzenstein, a leading authority in pulmonary pathology, has brought a pattern-based approach to formulating diagnoses in non-neoplastic lung diseases with the non-expert pulmonary pathologist in mind. Chapters are organized according to pattern of lung involvement with the idea that once the pattern is recognized the pathologist can easily find examples and review the relevant disease within the corresponding chapter. Filled with tips and key features to navigate differential diagnosis, Diagnostic Atlas of Non-Neoplastic Lung Disease is an indispensable guide for pathologists who encounter non-neoplastic lung specimens in the lab.

    Key Features:

    • Written by a respected pulmonary pathologist with over 40 years‚Äô experience in the lab
    • Over 350 high quality illustrative photomicrographs, many with low and high magnification views
    • Emphasizes a pattern-based approach for formulating diagnoses
    • Provides helpful tips for establishing diagnosis and avoiding misdiagnosis
    • Relevant clinical information including patient demographics, presenting manifestations, and radiographic findings where important for pathologic diagnosis

    Product Details

    • Publication Date June 17, 2016
    • Page Count 352
    • Product Form Hardback
    • ISBN 13 9781620700648
    • EISBN

    Table of Contents

    List of Abbreviations



    1. Normal Lung, Common Artifacts, and Incidental Findings

    Normal Lung Architecture

    Handling of Tissue Specimens

    Approach to Diagnosis


    Incidental Findings

    2. Interstitial Diseases I: Cellular Variants

    Cellular Nonspecific Interstitial Pneumonia (NSIP)

    Hypersensitivity Pneumonia (HP)

    Lymphoid Interstitial Pneumonia (LIP)

    Langerhans Cell Histiocytosis (LCH)


    Lymphangiomyomatosis (LAM)

    Diffuse Meningotheliomatosis

    3. Interstitial Diseases II: Fibrotic Variants

    Usual Interstitial Pneumonia (UIP)

    Fibrotic Nonspecific Interstitial Pneumonia (NSIP)

    Scarred Langerhans Cell Histiocytosis (LCH)

    Smoking-Related Interstitial Fibrosis (SRIF)

    Collagen Vascular Disease-Associated Interstitial Fibrosis

    Nonclassifiable Interstitial Fibrosis

    Rare, Unproven Entities

    Pleuroparenchymal Fibroelastosis (PPFE)

    Bronchiolocentric Interstitial Pneumonia

    4. Airspace-Predominant Diseases

    Organizing Pneumonia (OP)

    Eosinophilic Pneumonia

    Aspiration Pneumonia

    Exogenous Lipoid Pneumonia

    Respiratory Bronchiolitis Interstitial Lung Disease/Desquamative Interstitial Pneumonia (RBILD/DIP)

    Alveolar Hemorrhage Syndromes

    Pulmonary Alveolar Proteinosis (PAP)

    Pulmonary Alveolar Microlithiasis (PAM)

    5. Diffuse Alveolar Damage, Acute Interstitial Pneumonia

    Diffuse Alveolar Damage (DAD)

    Acute Interstitial Pneumonia (AIP)

    6. Necrotizing Noninfectious Diseases

    Granulomatosis With Polyangiitis (GPA)

    Eosinophilic Granulomatosis With Polyangiitis (EGPA) (Formerly Churg–Strauss Syndrome) (CSS)

    Necrotizing Sarcoid Granulomatosis (NSG)

    Bronchocentric Granulomatosis (BCG)

    Rheumatoid Nodule

    Lymphomatoid Granulomatosis (LYG)

    7. Infections I: Nongranulomatous Pneumonias

    Viral Pneumonia

    Cytomegalovirus Pneumonia (CMV)

    Herpes Simplex/Varicella-Zoster Pneumonia

    Adenovirus Pneumonia

    Measles Pneumonia

    Influenza and Other Viral Pneumonias

    Fungal Pneumonia

    Invasive Aspergillosis/Mucormycosis

    Candida Pneumonia


    Pneumocystis Pneumonia

    Bacterial Pneumonia



    Legionnaires’ Disease

    Rhodococcus Equi Pneumonia/Malakoplakia

    8. Infections II: Granulomatous Infections

    Evaluation of Necrotizing Granulomas






    Nontuberculous Mycobacterial Infections

    Dirofilarial Nodule (Dog Heartworm Disease)

    9. Pneumoconiosis



    Nodular Silicosis

    Acute Silicosis

    Mixed Dust Pneumoconiosis

    Hard Metal Pneumoconiosis

    Miscellaneous Pneumoconiosis


    Talc Pneumoconiosis (Talcosis)

    Coal Workers’ Pneumoconiosis (CWP)



    Flock Workers’ Lung

    10. Pulmonary Hypertension and Other Noninflammatory Vascular Disorders

    Pulmonary Hypertension—General Features

    Pulmonary Arterial Hypertension

    Primary Pulmonary Hypertension (PPH)

    Thrombotic/Thromboembolic Pulmonary Hypertension

    Embolic Pulmonary Hypertension

    Intravenous Drug Abusers’ Lung (Talc Granulomatosis)

    Other Emboli

    Other Causes of Pulmonary Arterial Hypertension

    Pulmonary Venous Hypertension

    Pulmonary Veno-Occlusive Disease (PVOD)

    Extrapulmonary Venous Obstruction

    Pulmonary Capillary Hemangiomatosis

    Pulmonary Emboli


    Other Emboli

    11. Large and Small Airway Diseases



    Middle Lobe Syndrome

    Mucoid Impaction of Bronchi (MIB)

    Tracheobronchial Amyloidosis

    Tracheobronchopathia Osteochondroplastica (TO)

    Respiratory Bronchiolitis (RB)

    Follicular Bronchiolitis

    Diffuse Panbronchiolitis

    Acute Cellular Bronchiolitis

    Constrictive Bronchiolitis Obliterans (CBO)

    Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH)

    12. Miscellaneous Nodules, Depositions, and Cysts

    Pulmonary Hyalinizing Granuloma (PHG)/Fibrosing Mediastinitis (FM)

    Amyloid Nodule (Nodular Amyloidosis)

    Nodular Lymphoid Hyperplasia/Inflammatory Pseudotumor

    Intraparenchymal Lymph Node

    Pulmonary Infarct

    Round Atelectasis

    Pulmonary Apical Cap

    Alveolar Septal Amyloidosis

    Metastatic Calcification

    Metaplastic Ossification

    Blebs, Bullae, Other Cysts, and Pneumothorax-Related Changes

    Blebs and Bullae

    Other Cysts

    Pneumothorax-Related Changes

    13. Pediatric Disorders

    Pulmonary Sequestration

    Intralobar Sequestration

    Extralobar Sequestration

    Congenital Cystic Adenomatoid Malformation (CCAM)/Congenital Pulmonary Airway Malformation (CPAM)

    Bronchogenic Cyst

    Congenital Pulmonary Overinflation (Emphysema)

    Pulmonary Interstitial Emphysema

    Congenital Pulmonary Lymphangiectasis

    Diffuse Lymphangiomatosis

    Interstitial Lung Disease in Children

    Bronchopulmonary Dysplasia (BPD) (Chronic Neonatal Lung Disease)

    Chronic Pneumonitis of Infancy (CPI)

    Pulmonary Interstitial Glycogenosis (PIG)

    Interstitial Pneumonias

    Neuroendocrine Cell Hyperplasia of Infancy (NEHI)/Persistent Tachypnea of Infancy