Neoplastic Mimics in Soft Tissue and Bone Pathology

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Sample Chapter: Chapter 1

Neoplastic Mimics in Soft Tissue and Bone Pathology

SKU# 9781620700518

Author: Vickie Y. Jo MD, Jason L. Hornick MD, PhD

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Description

Neoplastic mimics, or "pseudotumors," can simulate neoplasms on all levels of analysisóclinical, radiologic, and pathologicóand thus represent particular diagnostic pitfalls for the pathologist that can ultimately lead to therapeutic misdirection.

This book provides the pathologist with detailed morphologic descriptions and diagnostic guidance in recognizing these neoplastic mimics as they occur in soft tissue and bones. In addition, descriptions and diagnostic guidance are provided for the range of lesions that are considered benign neoplasms but may mimic malignant tumors. Throughout the book comparisons of neoplastic mimics with true neoplasms (and benign neoplasms with sarcomas) are provided, at clinical, gross, and histologic levels. In the presentation of every entity, the points that contribute to differential diagnosis are emphasized.

More than 300 color images and analysis of neoplastic and malignant mimics guide the pathologist through recognizing and distinguishing the unusual variants, morphologic anomalies and misleading features that may easily lead to an inaccurate interpretation and missed diagnosis. Because many of the entities described are uncommon, Neoplastic Mimics in Soft Tissue and Bone Pathology emphasizes imaging and clinical correlations throughout to support the pathologist as consultant to the entire diagnostic and clinical management team. Every pathologist who sees soft tissue and bone cases will find this book an invaluable working tool to ensure accurate diagnosis.

Neoplastic Mimics in Soft Tissue and Bone Pathology Features:

  • Over 300 high-quality images showing the full range of neoplastic and malignant mimics in soft tissue and bone specimens
  • Concise, specific text descriptions make the book easy to use as a visual reference
  • Expert authors guide the reader to recognizing and distinguishing misleading specimens

Product Details

  • Publication Date November 05, 2015
  • Page Count 192
  • Product Form Hardback
  • ISBN 13 9781620700518
  • EISBN

About The Author(s)

Assistant Professor of Pathology, Department of Pathology, Brigham & Women's Hospital, Harvard Medical School, Boston, MassachussettsDirector of Surgical Pathology, Director, Immunohistochemistry Laboratory, Brigham and Women's Hospital, Associate Professor of Pathology, Harvard Medical School, Boston, Massachussetts

Table of Contents

Contents

Preface

Acknowledgments

1. NEOPLASTIC MIMICS: GENERAL CONSIDERATIONS

Introduction

Philosophical and Practical Issues

Topographic Distribution and Biologic Nature of Neoplastic Mimics

Idiopathic Neoplastic Mimics

Reparative/Posttraumatic Neoplastic Mimics

Developmental Neoplastic Mimics

“Functional” Neoplastic Mimics

Iatrogenic Neoplastic Mimics

Infectious Neoplastic Mimics

2. GENERAL CONSIDERATIONS IN SOFT TISSUE AND BONE PATHOLOGY

3. MIMICS OF ADIPOCYTIC NEOPLASMS

Fat Necrosis

Intramuscular Angioma

Sclerosing Mesenteritis

Silicone Reaction

Massive Localized Lymphedema

Prolapsed Orbital Fat

Myelolipoma

Lipoma (Including Intramuscular Lipoma and Lipomatosis)

Spindle Cell Lipoma/Pleomorphic Lipoma

Hibernoma

Lipoblastoma

4. MIMICS OF FIBROBLASTIC/MYOFIBROBLASTIC AND FIBROHISTIOCYTIC NEOPLASMS

Mimics of Fibroblastic/Myofibroblastic Neoplasms

Nodular Fasciitis

Proliferative Fasciitis/Proliferative Myositis

Ischemic Fasciitis

Fibroma of Tendon Sheath

Desmoid Fibromatosis

Pseudosarcomatous Myofibroblastic Proliferation

Dermatomyofibroma

Cellular Benign Fibrous Histiocytoma

Mammary-Type Myofibroblastoma

Cellular Angiofibroma

Soft Tissue Perineurioma

Superficial Angiomyxoma

Intramuscular Myxoma (Including Cellular Myxoma)

Selected Mimics of Pediatric Fibroblastic/Myofibroblastic Neoplasms

Fibrous Hamartoma of Infancy

Infantile Myofibromatosis

Mimics of Fibrohistiocytic Neoplasms

Reactive and Inflammatory Processes

Cellular Neurothekeoma

Cellular Benign Fibrous Histiocytoma

5. MIMICS OF SMOOTH MUSCLE AND SKELETAL MUSCLE NEOPLASMS

Mimics of Smooth Muscle Neoplasms

Myopericytoma/Myofibroma

Pseudosarcomatous Myofibroblastic Proliferation

Angioleiomyoma

Cellular Schwannoma

EBV-Associated Smooth Muscle Neoplasms

Mimics of Skeletal Muscle Neoplasms

Crystal Storing Histiocytosis

Hibernoma

Granular Cell Tumor

Proliferative Fasciitis/Proliferative Myositis

Fetal Rhabdomyoma

6. MIMICS OF VASCULAR NEOPLASMS

Intravascular Papillary Endothelial Hyperplasia

Reactive Angioendotheliomatosis

Epithelioid Angiomatous Nodule

Bacillary Angiomatosis

Symplastic Hemangioma

Microvenular Hemangioma

Hobnail Hemangioma

Pseudoangiomatous Stromal Hyperplasia

Perilobular Hemangioma

Anastomosing Hemangioma of the Genitourinary Tract

Vascular Transformation of Lymph Node Sinuses

Spindle Cell Hemangioma

Epithelioid Hemangioma of Soft Tissue and Bone

Splenic Hemangioma and Littoral Cell Angioma

Atypical Postradiation Vascular Proliferation

Kaposi Sarcoma

7. MIMICS OF NEUROECTODERMAL NEOPLASMS

Traumatic Neuroma

Solitary Circumscribed Neuroma

Degenerative Atypia in Schwannoma (and Other Benign Nerve Sheath Tumors)

Cellular Schwannoma

Epithelioid Schwannoma

Diffuse Neurofibroma

Plexiform Neurofibroma

Hybrid Nerve Sheath Tumors

8. MIMICS OF NEOPLASMS OF UNCERTAIN DIFFERENTIATION AND GASTROINTESTINAL STROMAL TUMORS

Mimics of Neoplasms of Uncertain Differentiation

Atypical Fibroxanthoma

Angiomyofibroblastoma

Granuloma Annulare

Aneurysmal, Cellular, and Deep Variants of Fibrous Histiocytoma

Soft Tissue Chondroma

Cellular Neurothekeoma

Myoepithelioma of Soft Tissue

Schwannoma

Mimics of Gastrointestinal Stromal Tumors

Schwannoma

Leiomyoma

9. MIMICS OF OSSEOUS NEOPLASMS

Myositis Ossificans

Giant Cell Reparative Granuloma

Giant Cell Tumor of Bone

Aneurysmal Bone Cyst

Osteoid Osteoma and Osteoblastoma

Subungal Exostosis

Bizarre Parosteal Osteochondromatous Proliferation

Osteochondroma

Fibrous Dysplasia

Desmoplastic Fibroma

10. MIMICS OF CARTILAGINOUS NEOPLASMS

Osteochondroma

Chondroma

Chondromyxoid Fibroma

Chondroblastoma

Bizarre Parosteal Osteochondromatous Proliferation

Synovial Chondromatosis

References

Index