Radiobiology Self-Assessment Guide

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Sample Chapter: Chapter 1

Radiobiology Self-Assessment Guide

SKU# 9781620701140

Author: Jennifer Yu MD, PhD, Mohamed Abazeed MD, PhD

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    Radiobiology Self-Assessment Guide--a companion to the Radiation Oncology Self-Assessment Guide and Physics in Radiation Oncology Self-Assessment Guide--is a comprehensive review for practitioners of radiation oncology looking to enhance their knowledge of radiobiology. It covers in depth the principles of radiobiology as applied to radiation oncology along with their clinical applications. To foster retention of key concepts and data, the resource utilizes a user-friendly "flash card" question and answer format with over 700 questions. The questions are supported by detailed answers and rationales along with reference citations for source information.

    The guide is comprised of 29 chapters and cover topics commonly found on the radiation and cancer biology portion of the radiation oncology board examination. Aspects of basic radiobiology covered include fundamentals such as cell cycle, cell survival curves and interactions of radiation with matter, and acute and long-term sequelae of radiation. Modern concepts such as immunotherapy, radiogenomics, and normal and cancer stem cells are also included. Focused and authoritative, this must-have review provides the expertise of faculty from the Department of Radiation Oncology at the Cleveland Clinic Taussig Cancer Institute and Lerner Research Institute.

    Key Features:

    • Provides a comprehensive study guide for the Radiation and Cancer Biology portion to the Radiation Oncology Board Exam
    • Includes more than 700 questions with detailed answers and rationales on flip pages for easy, flash card-like review
    • Includes essential review of cancer biology concepts such as immunotherapy, stem cells, gene therapy, chemotherapy and targeted agents
    • Content provided by a vast array of contributors, including attending radiation oncology physicians, physicists, and radiation oncology residents

    Product Details

    • Publication Date November 23, 2016
    • Page Count 520
    • Product Form Paperback / softback
    • ISBN 13 9781620701140
    • EISBN

    Table of Contents




    1. Interaction of Radiation With Matter

    John F. Greskovich, Jr., Mihir Naik, and Marc Apple

    2. Cell Survival Curves and Cell Death

    Ehsan H. Balagamwala, C. Marc Leyrer, Jeffrey A. Kittel, and Alex Almasan

    3. DNA, Chromosome and Chromatid Damage, Repair, and Measurement

    Ehsan H. Balagamwala, C. Marc Leyrer, Jeffrey A. Kittel, and Alex Almasan

    4. Radiosensitivity and the Dose-Rate Effect

    Brian D. Yard and Mohamed E. Abazeed

    5. Radiation Damage Repair and Models for Normal Tissues

    Aditya Juloori, Choamei Xiang, Michael A. Weller, and Jennifer S. Yu

    6. Hypoxia, Oxygen, Reoxygenation, and Angiogenesis

    Xingjiang Yu, Jennifer S. Yu, and Eli Bar

    7. Linear Energy Transfer and Relative Biological Effectiveness

    Yvonne Pham and Chirag Shah

    8. Assays for Cell, Tissue, and Solid Tumors

    C. Marc Leyrer, Ehsan H. Balagamwala, and Camille Berriochoa

    9. Molecular Techniques, Assay Systems, and Signaling in Radiobiology

    Kailin Yang and Jennifer S. Yu

    10. Biology of Cancer

    Kailin Yang and Jennifer S. Yu

    11. Model Tumor Systems and Predictive Assays

    C. Marc Leyrer, Camille Berriochoa, and Ehsan H. Balagamwala

    12. Cell Kinetics

    Matthew C. Ward and Richard Blake Ross

    13. Factors Influencing Tumor Control and Complications

    Daesung Lee

    14. Impact of Time, Dose, and Fractionation in Radiation Oncology

    Daesung Lee

    15. Effects of Total Body Irradiation

    Sudha Amarnath

    16. Radiation Sensitizers, Radioprotectors, and Bioreductive Drugs

    Aditya Juloori and Michael A. Weller

    17. Radiation Carcinogenesis

    Bindu V. Manyam and Michael A. Weller

    18. Effects of Radiation on Hereditary Damage, Mutations, and Chromosome Aberrations

    Camille Berriochoa, C. Marc Leyrer, and Anthony Mastroianni

    19. Effects of Radiation on the Embryo and Fetus

    Yvonne Pham and Steven Oh

    20. Doses and Risks in Nonradiation Oncology Subspecialties

    Frank Dong, Kevin Wunderle, and Salim Balik

    21. Radiation Protection

    Taoran Cui and Peng Qi

    22. Alternative Radiation Therapy Modalities

    Susan Kost and Andrew Godley

    23. Brachytherapy and Stereotactic Radiosurgery

    Sudha Amarnath

    24. Gene Therapy

    HyeonJoo Cheon

    25. Chemotherapy and Targeted Agents

    Nikhil Joshi and Neil Woody

    26. Hyperthermia

    Sharvari Dharmaiah, Vinay Rao, and Jennifer S. Yu

    27. Stem Cells

    Haidong Huang and Jennifer S. Yu

    28. Immunotherapy

    Nikhil Joshi and Neil Woody

    29. Radiogenomics

    Mohamed E. Abazeed